Pyridine is a basic heterocyclic organic compound with the chemical formula C5H5N. It is structurally related to benzene, with one methine group (=CH−) replaced by a nitrogen atom. 5315-25-3, formula is C6H6BrN, Name is 2-Bromo-6-methylpyridine. It is a highly flammable, weakly alkaline, water-miscible liquid with a distinctive, unpleasant fish-like smell. Application In Synthesis of 5315-25-3.
Guo, Shi-Yu;Yang, Fan;Song, Ting-Ting;Guan, Yu-Qing;Min, Xiang-Ting;Ji, Ding-Wei;Hu, Yan-Cheng;Chen, Qing-An research published 《 Photo-induced catalytic halopyridylation of alkenes》, the research content is summarized as follows. Here an atom-economical cross-coupling of halopyridines such as 2-chloropyridine, 2-iodopyridine, 2-bromo-6-methylpyridine, etc. and unactivated alkenes such as hex-1-ene, cyclopentene, ethenylcyclohexane, etc. under photo-redox catalysis to afford a series of alkene halopyridylation products e.g., I was reported. This protocol with mild and redox neutral conditions contributes broad substrate scope. As a complement to conventional Heck-type reaction, this radical process avoids the involvement of β-H elimination and thus useful pyridyl and halide groups could be simultaneously and regioselectively incorporated onto alkenes. The success depends on TFA-promoted domino photocatalytic oxidative quenching activation and radical-polar crossover pathway. Plausible mechanism is proposed based on mechanistic investigations. Moreover, the reserved C-X bonds of these products are beneficial for performing further synthetic elaborations.
Application In Synthesis of 5315-25-3, 2-Bromo-6-methylpyridine (2BMPy) is a bromopyridine derivative. It is formed when 2-chloro-6-methylpyridine is heated with bromotrimethylsilane. Its synthesis from various methods have been reported.
2-Bromo-6-methylpyridine is a building block in the preparation of nitrogen containing heterocyclic compounds.
2-Bromo-6-methylpyridine is an organic compound that belongs to the group of pyridinium halides. It is soluble in common solvents such as water, ethanol, and acetone. 2BMPy has been shown to act as a glutamate receptor antagonist and has been used in the study of glutamate receptors, including their subtypes. This chemical has also been shown to have antioxidant properties and can be used in the prevention of atherosclerosis., 5315-25-3.