Guo, Siyu published the artcileComparative efficacy of danshen class injections for treating acute coronary syndrome: a multidimensional Bayesian network meta-analysis of randomized controlled trials, Product Details of C17H18N2O6, the main research area is meta analysis danshen class injection acute coronary syndrome; Danshen class injections; acute coronary syndrome; network meta-analysis; outcomes research; randomized controlled trials.
Acute coronary syndrome, that is a common and serious cardiovascular disease, imposes a huge economic burden on global public health. And Danshen class injections are commonly used in the treatment of acute coronary syndrome in China. Thus, the Bayesian network meta-anal. was devised to investigate the efficacy of different Danshen class injections against acute coronary syndrome. Eligible inclusion and exclusion criteria were established in advance. Then, a systematic literature search was performed in several databases from inception to Feb. 2020. Further, the included randomized controlled trials data were adopted to calculation, prepare graphs and multidimensional cluster anal. by WinBUGS 1.4.3, Stata V.13.0 and R 3.6.1 software, resp. A total of 53 eligible randomized controlled trial studies with 6401 patients were obtained that evaluated the clin. effectiveness rate, the level of hypersensitive C-reactive protein, C-reactive protein, interleukin-6, fibrinogen, and adverse reactions after the application of Danshen class injections plus western medicine. Compared with western medicine alone, Danshen class injections combined with western medicine therapy were associated with significantly improved the therapeutic effect. In addition, the results of the multidimensional cluster anal. demonstrated that Danhong injection + western medicine and Danshen injection + western medicine had better therapeutic effects. However, since most eligible randomized controlled trial studies did not focus on the monitoring of adverse reactions, the safety of these Chinese herbal injections needs to be further explored. Based on this Bayesian network meta-anal. results, Danhong injection + western medicine and Danshen injection + western medicine might have a better impact on acute coronary syndrome patients. Nevertheless, more large samples, high-quality clin. and multicenter randomized controlled trial studies should be tested and verified in the future.
Frontiers in Pharmacology published new progress about C-reactive protein Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 21829-25-4 belongs to class pyridine-derivatives, name is Dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate, and the molecular formula is C17H18N2O6, Product Details of C17H18N2O6.