Guo, Zi-Qiong; Xu, Hui; Wang, Xing; Wang, Zhen-Yu; Ma, Biao; Dai, Hui-Xiong published the artcile< C3-Arylation of indoles with aryl ketones via C-C/C-H activations>, Application In Synthesis of 1428537-19-2, the main research area is arylindole preparation regioselective; indole aryl ketone arylation palladium catalyst carbon hydrogen activation.
C3-Arylation of indoles with aryl ketones is accomplished via palladium-catalyzed ligand-promoted Ar-C(O) cleavage and subsequent C-H arylation of indole. Various (hetero)aryl ketones are compatible in this reaction, affording the corresponding 3-arylindoles in moderate to good yields. Further introduction of an indole moiety into the natural products desoxyestrone and evodiamine demonstrate the synthetic utility of this protocol.
Chemical Communications (Cambridge, United Kingdom) published new progress about Aryl ketones Role: RCT (Reactant), RACT (Reactant or Reagent). 1428537-19-2 belongs to class pyridine-derivatives, and the molecular formula is C13H15F3N2O, Application In Synthesis of 1428537-19-2.