Hara, Naofumi; Aso, Koki; Li, Qiao-Zhi; Sakaki, Shigeyoshi; Nakao, Yoshiaki published the artcile< C2-selective alkylation of pyridines by rhodium-aluminum complexes>, Application of C11H16BNO2, the main research area is pyridine alkylation alkene vinylsilane CH activation rhodium aluminum catalyst; alkylpyridine preparation alkylation CH activation vinylsilane alkene bimetallic catalyst.
A C2- and mono-selective alkylation of various pyridines and azines with unactivated alkenes and vinylarenes using a heterobimetallic Rh-Al catalyst is reported. The use of aliphatic alkenes exclusively affords the linear alkylation products, while vinylarenes mainly afford branched alkylation products. The details of the reaction mechanism are revealed by DFT calculations: the reductive elimination of the products is rate-determining, which is consistent with the exptl. results. The origin of the linear/branched selectivity is elucidated based on deformation/interaction anal.
Tetrahedron published new progress about Alkenes Role: RCT (Reactant), RACT (Reactant or Reagent). 329214-79-1 belongs to class pyridine-derivatives, and the molecular formula is C11H16BNO2, Application of C11H16BNO2.