Heerding, Dirk published the artcileSynthesis of a tritium labeled analog of the novel hematoregulatory agent SB 209978, Recommanded Product: Methyl 4-chloropicolinate, the main research area is SB 209978 tritium preparation; hematoregulatory agent tritium labeled preparation.
[3H]-SB 209978 (I, X = 3H) was synthesized in 6 steps from phenylene diamine dihydrochloride. A key aspect was the regioselective synthesis of 6-chloropicolinic acid. This was condensed with diamine II and the resulting product was deprotected to give I (X = Cl). Palladium catalyzed 3H-hydrogenolysis of the chloropyridine rings gave the final product I (3H).
Journal of Labelled Compounds & Radiopharmaceuticals published new progress about SB 209978 tritium preparation; hematoregulatory agent tritium labeled preparation. 24484-93-3 belongs to class pyridine-derivatives, name is Methyl 4-chloropicolinate, and the molecular formula is C7H6ClNO2, Recommanded Product: Methyl 4-chloropicolinate.