Ho, Dang Binh; Gargaro, Samantha; Klake, Raphael K.; Sieber, Joshua D. published the artcile< Development of a Modified System to Provide Improved Diastereocontrol in the Linear-Selective Cu-Catalyzed Reductive Coupling of Ketones and Allenamides>, Formula: C7H7NO, the main research area is chiral gamma lactone preparation; ketone allenamide reductive coupling linear selective copper.
Chiral γ-lactones are prevalent organic architectures found in a large array of natural products. In this work, authors disclose the development of a modified catalytic system utilizing a com. available Cu-phosphite catalyst for the diastereoselective reductive coupling of chiral allenamides and ketones to afford chiral γ-lactone precursors in 80:20 to 99:1 dr.
Journal of Organic Chemistry published new progress about Amides Role: RCT (Reactant), RACT (Reactant or Reagent) (allenamides). 350-03-8 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO, Formula: C7H7NO.