Recently I am researching about HORIUTI-POLANYI MECHANISM; STABILIZED PALLADIUM NANOPARTICLES; COPD BIOMARKER DESMOSINE; HETEROGENEOUS CATALYSIS; CARBOXYLIC-ACIDS; IONIC LIQUIDS; AMINES; WATER; HYDRODEHALOGENATION; TRANSFORMATION, Saw an article supported by the JSPS KAKENHIMinistry of Education, Culture, Sports, Science and Technology, Japan (MEXT)Japan Society for the Promotion of ScienceGrants-in-Aid for Scientific Research (KAKENHI) [JP17K01953, JP20K05734]. Name: Phenyl(pyridin-2-yl)methanone. Published in WILEY-V C H VERLAG GMBH in WEINHEIM ,Authors: Tanaka, N; Usuki, T. The CAS is 91-02-1. Through research, I have a further understanding and discovery of Phenyl(pyridin-2-yl)methanone
Hydrogenation of over a dozen aromatic compounds, including both heteroarenes and arenes, over palladium on carbon (Pd/C, 1-100 mol%) with H-2-balloon pressure at room temperature is reported. Analyses using pyridine as a model substrate revealed that acetic acid was the best solvent, as using only 1 mol% Pd/C provided piperidine quantitatively. Substrate scope analysis and density functional theory calculations indicated that reaction rates are highly dependent on frontier molecular orbital characteristics and the steric bulkiness of substituents. Moreover, the established method was used for the concise synthesis of the anti-Alzheimer drug donepezil (Aricept (R)).
Name: Phenyl(pyridin-2-yl)methanone. About Phenyl(pyridin-2-yl)methanone, If you have any questions, you can contact Tanaka, N; Usuki, T or concate me.
Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem