At 25 °C pyridine has a viscosity of 0.88 mPa/s and thermal conductivity of 0.166 W·m−1·K−1. 1603-41-4, formula is C6H8N2, Name is 2-Amino-5-methylpyridine. The enthalpy of vaporization is 35.09 kJ·mol−1 at the boiling point and normal pressure.The enthalpy of fusion is 8.28 kJ·mol−1 at the melting point. Computed Properties of 1603-41-4.
Hsu, Kai-Cheng;Chu, Jung-Chun;Tseng, Hui-Ju;Liu, Chia-I.;Wang, Hao-Ching;Lin, Tony Eight;Lee, Hong-Sheng;Hsin, Ling-Wei;Wang, Andrew H.-J.;Lin, Chien-Huang;Huang, Wei-Jan research published 《 Synthesis and biological evaluation of phenothiazine derivative-containing hydroxamic acids as potent class II histone deacetylase inhibitors》, the research content is summarized as follows. In this study, the acridine ring was modified using various phenothiazine derivatives Several resulting compounds I [R = H, Br, H2NCO, etc.; R1 = hydroxycarbamoyl, 3-(hydroxyamino)-3-oxo-prop-1-enyl; X = S, sulfinyl] exhibited potent enzyme-inhibiting activity towards class II HDACs when compared to the clin. approved HDAC inhibitor SAHA. Compound I [R = H2NCO; R1 = hydroxycarbamoyl; X = S] demonstrated the highest class II HDAC inhibition (IC50 = 4.6-600 nM), as well as promotion of neurite outgrowth. Importantly, compound I [R = H2NCO; R1 = hydroxycarbamoyl; X = S] displayed no cytotoxicity against neuron cells. Compound I [R = H2NCO; R1 = hydroxycarbamoyl; X = S] was further evaluated for cellular effects. Altogether, these findings showed a potential strategy in HDAC inhibition for treatment of the neurol. disease.
Computed Properties of 1603-41-4, 2-Amino-5-methylpyridine, also known as 2-Amino-5-methylpyridine, is a useful research compound. Its molecular formula is C6H8N2 and its molecular weight is 108.14 g/mol. The purity is usually 95%.
2-Amino-5-methylpyridine is a chemical compound that belongs to the group of methyl ketones. It has a nitrogen atom and an oxygen atom in its structure, which allows it to form hydrogen bonds with other molecules. 2-Amino-5-methylpyridine can be obtained by reacting hydrochloric acid and xanthone in the presence of a base. The compound is highly reactive and has been shown to have antiinflammatory properties. This can be attributed to its ability to inhibit prostaglandin synthesis. 2-Amino-5-methylpyridine also has fluorescence properties that are sensitive to pH changes and can be used as a probe for metal ions. 2-Amino-5-methylpyridine is an organic compound that contains a methyl group, two nitrogen atoms, and one oxygen atom in its chemical structure. This molecule can form hydrogen bonds with other molecules due to its nitrogen atoms and oxygen atom,, 1603-41-4.