In 2018,Hu, Li-Qun; Deng, Rong-Li; Li, Yan-Fen; Zeng, Cui-Jin; Shen, Dong-Sheng; Liu, Feng-Shou published 《Developing Bis(imino)acenaphthene-Supported N-Heterocyclic Carbene Palladium Precatalysts for Direct Arylation of Azoles》.Organometallics published the findings.Category: pyridine-derivatives The information in the text is summarized as follows:
From the strategy of developing highly efficient protocol for Pd-catalyzed cross-coupling reactions, bulky bis(imino)acenaphthene (BIAN)-supported Pd-PEPPSI complexes were synthesized, characterized and applied in direct arylation of azoles. The effect of backbone and N-moieties on NHCs was evaluated and the reaction conditions were optimized. The bulky Pd-PEPPSI complexes could be successfully employed in cross-coupling of (hetero)aryl bromides with azoles at a low Pd loading of 0.5-0.05 mol% under aerobic conditions, demonstrating the ease of manipulation without glovebox and handling of solvents. In the experiment, the researchers used many compounds, for example, 5-Bromo-2-chloropyridine(cas: 53939-30-3Category: pyridine-derivatives)
5-Bromo-2-chloropyridine(cas: 53939-30-3) belongs to pyridine. Pyridine and its simple derivatives are stable and relatively unreactive liquids, with strong penetrating odours that are unpleasant.Category: pyridine-derivatives