In 2022,Hua, Manli; Song, Jinliang; Huang, Xin; Fan, Honglei; Wu, Tianbin; Meng, Qinglei; Zhang, Zhanrong; Han, Buxing published an article in Chemical Science. The title of the article was 《Highly efficient C(CO)-C(alkyl) bond cleavage in ketones to access esters over ultrathin N-doped carbon nanosheets》.Name: 4-Acetylpyridine The author mentioned the following in the article:
A series of porous and ultrathin N-doped carbon nanosheets (denoted as CN-X, where X represents the pyrolysis temperature) as heterogeneous metal-free catalysts was reported. It was observed that the fabricated CN-800 could efficiently catalyze the oxidative cleavage of the C(CO)-C bond in various ketones RC(O)CH3 [R = Ph, naphthalen-1-yl, thiophen-2-yl, pyridin-4-yl, etc.] to generate the corresponding Me esters RC(O)OCH3 at 130°C without using any addnl. base. Detailed investigations revealed that the higher content and electron d. of the graphitic-N species contributed to the excellent performance of CN-800. The high surface area affording active sites that are more easily accessed, could also enhance the catalytic activity. The catalysts have great potential for practical applications because of some obvious advantages, such as low cost, neutral reaction conditions, heterogeneous nature, high efficiency, and broad ketone scope. This is the first work on efficient synthesis of Me esters via oxidative esterification of ketones over heterogeneous metal-free catalysts. After reading the article, we found that the author used 4-Acetylpyridine(cas: 1122-54-9Name: 4-Acetylpyridine)
4-Acetylpyridine(cas: 1122-54-9) belongs to pyridine. Pyridine is a relatively complex molecule and exhibits a number of different bands in IR spectra. Among others, the bands characterizing the ν8a and ν19b modes have been found to be sensitive to the coordination or protonation of the molecule. Note that the band that is diagnostic for the PyH+ ion at about 1545 cm− 1 (ν19b mode) does not overlap with any of the other bands.Name: 4-Acetylpyridine