Ingale, Ajit P.; Garad, Dnyaneshwar N.; Ukale, Dattatraya; Thorat, Nitin M.; Shinde, Sandeep V. published the artcile< Thiamine hydrochloride as a recyclable organocatalyst for the efficient and chemoselective N-tert-butyloxycarbonylation of amines>, Formula: C6H8N2, the main research area is amine tert butyloxycarbonylation chemoselective thiamine hydrochloride recyclable green organocatalyst.
Thiamine hydrochloride promoted highly efficient and ecofriendly approach has been described for the chemoselective N-tert-butyloxycarbonylation of amines under solvent-free conditions at ambient temperature The demonstrated approach has been applicable for the N-Boc protection of variety of aliphatic, aryl, heteroaryl amines. The chemoselective protection of amino group occurs in chiral amines and amino alc. without racemization in high yield. Thiamine hydrochloride is stable, economical, easy to handle and environmentally friendly.
Synthetic Communications published new progress about Amines Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 3731-53-1 belongs to class pyridine-derivatives, and the molecular formula is C6H8N2, Formula: C6H8N2.