I found the field of Chemistry very interesting. Saw the article Construction of Chiral beta-Trifluoromethyl Alcohols Enabled by Catalytic Enantioselective Aldol-Type Reaction of CF3CHN2 published in 2019.0. COA of Formula: C6H5NO, Reprint Addresses Zhang, FG; Ma, JA (corresponding author), Tianjin Univ, Dept Chem, Tianjin Key Lab Mol Optoelect Sci, Tianjin 300072, Peoples R China.; Zhang, FG; Ma, JA (corresponding author), Tianjin Univ, Tianjin Collaborat Innovat Ctr Chem Sci & Engn, Tianjin 300072, Peoples R China.; Ma, JA (corresponding author), Nankai Univ, State Key Lab Elementoorgan Chem, Tianjin 300071, Peoples R China.. The CAS is 500-22-1. Through research, I have a further understanding and discovery of 3-Pyridinecarboxaldehyde
A zinc-/quinine-mediated enantioselective Aldol-type reaction of trifluorodiazoethane (CF3CHN2) with various aldehydes is described. This study demonstrated the feasibility of utilizing CF3CHN2 as an effective hard nucleophile in catalytic asymmetric transformations. Furthermore, the synthetic utility of this protocol is exemplified by the construction of a diverse set of chiral beta-trifluoromethylated alcohols, including a valuable HDAC inhibitor precursor.
About 3-Pyridinecarboxaldehyde, If you have any questions, you can contact Rong, MY; Yang, LJ; Nie, J; Zhang, FG; Ma, JA or concate me.. COA of Formula: C6H5NO
Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem