Related Products of 16179-97-8, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 16179-97-8, name is 2-(Pyridin-2-yl)acetic acid hydrochloride, molecular formula is C7H8ClNO2, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.
4.1 Synthesis of bis(2-carboxymethylpyridinium) hexafluorosilicate, (I) 2-Pyridineacetic acid hydrochloride (L1 ? HCl; 5.21 g, 0.003 mol) was dissolved in boiling methanol (250 mL) and to the obtained solution the fluorosilicic acid (FSA, 45%, 2.7 mL, molar ratio L1 ? HCl: FSA = 1: 3) was added. A reaction mixture stored at ambient conditions prior to the beginning of crystallization of the reaction product (6.50 g, 81.9%). Colorless transparent crystals with the composition (L1H)2[SiF6] (I). Anal. found, %: Si 6.87, N 7.31, F 29.48. Calcd. for C14H16F6N2O4S?: Si 7.18, N 7.18, F 29.22. Mass spectrum: [ML1]+¡¤ (m/z = 137, I = 42%). IR-spectrum: 3337, 3257, 3053, 3025 [nu(N+H)], 1729, 1717, 1683 [nu(C = ?), delta(N+H)], 737 [nu(SiF)], 482, 405 [delta(SiF2)]. 19F NMR (282 MHz, D2O): delta = -132.59 ppm (s, SiF62-).
While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 16179-97-8, 2-(Pyridin-2-yl)acetic acid hydrochloride.
Reference:
Article; Gelmboldt, Vladimir O.; Anisimov, Vladimir Yu.; Shyshkin, Ivan O.; Fonari, Marina S.; Kravtsov, Victor Ch.; Journal of Fluorine Chemistry; vol. 205; (2018); p. 15 – 21;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem