Adding a certain compound to certain chemical reactions, such as: 1137-67-3, 2-(Pyridin-3-yl)-1H-benzo[d]imidazole, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, Formula: C12H9N3, blongs to pyridine-derivatives compound. Formula: C12H9N3
A solution of 2-(3-pyridyl)-1H-benzimidazole, L1, (0.34 g,1.79 mmol) in methanol (4 ml) was added to a solution ofZn(OAc)22H2O (0.39 g, 1.79 mmol) in methanol (6 ml).The mixture was stirred for 24 h at room temperature to give a white precipitate. After the reaction period, the precipitate was filtered off, washed with methanol (3 9 20 mL) and dried to afford complex 1 as a white solid. Yield = 0.39 g (58 %). 1H NMR (400 MHz,DMSO-d6): d(ppm): 13.15 (s, 1H, NH), 9.45 (d, 1H, 3JHH = 7.19 Hz, ArH), 8.76 (d, 1H, 3JHH = 7.29 Hz,ArH), 8.54 (d, 1H, 3JHH = 7.29 Hz, ArH), 7.61 (d, 2H,3JHH = 7.19 Hz, ArH), 7.21 (d, 2H, 3JHH = 7.30 Hz,ArH), 1.80 (s, 6H, CH3). IR m (cm-1): 3074.87 (weak, N-H), 1625 (strong, C=O), 1601 (medium, C=Npy), 1445(weak, ArH). (ESI-MS) m/z (%): 194 (M?-Zn2C8H13O8-L1, 100 %); 314 (M?-ZnC6H13O6L1, 8.0 %), 501 (M?-ZnC7H12O6, 8.2 %), 501(M?-C4H12, 8.2 %). Anal. Calcd.for C16H15N3O4Zn: C, 50.75; H, 3.99; N, 10.00. Found: C,50.60; H, 3.70; N, 9.65.
The synthetic route of 1137-67-3 has been constantly updated, and we look forward to future research findings.
Reference:
Article; Zaca, Thembisile P.; Ojwach, Stephen O.; Akerman, Matthew P.; Transition Metal Chemistry; vol. 41; 6; (2016); p. 663 – 673;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem