Adding a certain compound to certain chemical reactions, such as: 7295-76-3, 3-Methoxypyridine, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, 7295-76-3, blongs to pyridine-derivatives compound. Computed Properties of C6H7NO
General procedure: First, 10 mmol of the respective pyridine were dissolved in 50 mL of dried THF. After additionof 0.5 mmol of copper(I) iodide and 3 mL of dimethyl sulphide, the mixture was stirred at room temperature until a clear solution resulted. Then, it was cooled down to -20 C. After 15 min, 10 mmolof acetyl chloride were added dropwise and stirring continued for 15 min. Then, 10 mmol of phenylmagnesium chloride were added and stirring followed for additional 15 min. Then, the mixturewarmed up to room temperature. Then, 50 mL of an ammonium chloride solution (20%) were addedand extraction with diethyl ether followed with portions of 50, 25 and again 25 mL. The unified organiclayer was extracted with each 50 mL of a solution of ammonium chloride in ammonia for two times,with 50 mL water, hydrochloric acid (10%) for two times, water and finally a saturated solution ofsodium chloride in water. The organic layer was then dried over sodium sulphate, filtered and finallyremoved under reduced pressure to give an oily substance that partially crystallized from methanol.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,7295-76-3, its application will become more common.
Reference:
Article; Holzer, Max; Schade, Nico; Opitz, Ansgar; Hilbrich, Isabel; Stieler, Jens; Vogel, Tim; Neukel, Valentina; Oberstadt, Moritz; Totzke, Frank; Schchtele, Christoph; Sippl, Wolfgang; Hilgeroth, Andreas; Molecules; vol. 23; 9; (2018);,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem