Electric Literature of 867279-13-8, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 867279-13-8, name is 4-Bromo-2-chloro-5-methylpyridine. This compound has unique chemical properties. The synthetic route is as follows.
4-Bromo-2-chloro-5-methylpyridine (600 mg, 2.9 mmol) was added to a mixture of4-(tert-butyl)-1H-imidazole (431 mg, 3.48 mmol) and C52CO3 (2.83 g, 8.7 mmol) in DMF (2 mL). The resulting solution was stirred at 100C overnight. The mixture was cooled to rt, diluted with EtOAc (100 mL), and washed with water (3OmLx2) and brine (3OmL). The organic layer was dried over Na2504, filtered, and concentrated in vacuo. Purification of theresidue on a silica gel column with 30% EtOAc/PE provided 400 mg (55%) of 4-(4-(tert- butyl)- 1H-imidazol- 1 -yl)-2-chloro-5 -methyl pyridine as a light yellow solid.
While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 867279-13-8, 4-Bromo-2-chloro-5-methylpyridine.
Reference:
Patent; ENANTA PHARMACEUTICALS, INC.; WANG, Guoqiang; SHEN, Ruichao; LONG, Jiang; MA, Jun; XING, Xuechao; HE, Yong; GRANGER, Brett; HE, Jing; WANG, Bin; OR, Yat, Sun; (125 pag.)WO2018/209354; (2018); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem