Application of 876919-08-3, Adding some certain compound to certain chemical reactions, such as: 876919-08-3, name is Methyl 3-fluoroisonicotinate,molecular formula is C7H6FNO2, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 876919-08-3.
To a suspension ofPreparation 54A (480 mg, 2.7 mmol) in DMA (5 mL) was added methyl3-fluoroisonicotinate at rt. The reaction mixture was stirred at 170 oc for 1 h in a microwave. Concentration in vacuo followed by purification by silica gelchromatography gave 395 mg (47%) of the title compound as a yellow gum. [M+H]calc’d for C1sH19FNzOz, 315; found 315.
According to the analysis of related databases, 876919-08-3, the application of this compound in the production field has become more and more popular.
Reference:
Patent; QUANTICEL PHARMACEUTICALS, INC.; CHEN, Young, K.; KANOUNI, Toufike; NIE, Zhe; STAFFORD, Jeffrey, Alan; VEAL, James, Marvin; WALLACE, Michael, Brennan; WO2014/100818; (2014); A1;,
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