In 2019,Journal of Separation Science included an article by Jadda, Ramana; Madhumanchi, Sreenu; Suedee, Roongnapa. Product Details of 141-86-6. The article was titled 《Novel adsorptive materials by adenosine 5′-triphosphate imprinted-polymer over the surface of polystyrene nanospheres for selective separation of adenosine 5′-triphosphate biomarker from urine》. The information in the text is summarized as follows:
The authors have developed a method to assess ATP by adsorptive extraction using surface ATP-imprinted polymer over polystyrene nanoparticles (412 ± 16 nm) for selective recognition/separation from urine. Molecularly imprinted polymer was synthesized by emulsion copolymerization reaction using ATP as a template, functional monomers (methacrylic acid, N-iso-Pr acrylamide, and dimethylamino ethylmethacrylate) and a crosslinker, methylenebisacrylamide. The binding capacities of imprinted and non-imprinted polymers were measured using HPLC with UV detection with a detection limit of 1.6 ± 0.02μM of ATP in the urine. High binding affinity (QMIP, 42.65μmol/g), and high selectivity and specificity to ATP compared to other competitive nucleotides including ADP, AMP, and analogs such as adenosine, adenine, uridine, uric acid, and creatinine were observed The imprinting efficiency of imprinted polymer is 2.11 for urine (QMIP, 100.3μmol/g) and 2.51 for synthetic urine (QMIP, 48.5μmol/g). The extraction protocol was successfully applied to the direct extraction of ATP from spiked human urine indicating that this synthesized molecularly imprinted polymer allowed ATP to be preconcd. while simultaneously interfering compounds were removed from the matrix. These submicron imprinted polymers over nano polystyrene spheres have a potential in the pharmaceutical industries and clin. anal. applications. In the part of experimental materials, we found many familiar compounds, such as 2,6-Diaminopyridine(cas: 141-86-6Product Details of 141-86-6)
2,6-Diaminopyridine(cas: 141-86-6) belongs to pyridine. Pyridine and its simple derivatives are stable and relatively unreactive liquids, with strong penetrating odours that are unpleasant.Product Details of 141-86-6