Ruthenium-Catalyzed meta-CAr-H Bond Difluoroalkylation of 2-Phenoxypyridines was written by Jia, Chunqi;Wang, Shichong;Lv, Xulu;Li, Gang;Zhong, Lei;Zou, Lei;Cui, Xiuling. And the article was included in European Journal of Organic Chemistry in 2020.SDS of cas: 4783-68-0 This article mentions the following:
A ruthenium-catalyzed meta-selective CAr-H bond difluoroalkylation of 2-phenoxypyridine using 2-bromo-2,2-difluoroacetate has been developed. Mechanistic studies indicated that this difluoroalkylation might involve a radical process. Furthermore, a new method is reported for the synthesis of 2-(meta-difluoroalkylphenoxy)pyridine derivatives, which are present in many pharmaceuticals and other functional compounds In the experiment, the researchers used many compounds, for example, 2-Phenoxypyridine (cas: 4783-68-0SDS of cas: 4783-68-0).
2-Phenoxypyridine (cas: 4783-68-0) belongs to pyridine derivatives. Pyridine’s the lone pair does not contribute to the aromatic system but importantly influences the chemical properties of pyridine, as it easily supports bond formation via an electrophilic attack. Pyridine groups exist in countless molecules, and their applications include catalysis, drug design, molecular recognition, and natural product synthesis.SDS of cas: 4783-68-0