Triazolopyridines. 18. Nucleophilic substitution reactions of triazolopyridines; a new route to 2,2′-bipyridines was written by Jones, Gurnos;Pitman, Mark A.;Lunt, Edward;Lythgoe, David J.;Abarca, Belen;Ballesteros, Rafael;Elmasnaouy, Mostafa. And the article was included in Tetrahedron in 1997.Computed Properties of C6H6BrNO This article mentions the following:
The synthesis of some 5-, 6-, and 7-halotriazolopyridines and their reactions with nucleophiles are described. The formation of 7,7′-bitriazolopyridines provides a new synthesis of 2,2′-bipyridines. In the experiment, the researchers used many compounds, for example, (4-Bromopyridin-2-yl)methanol (cas: 131747-45-0Computed Properties of C6H6BrNO).
(4-Bromopyridin-2-yl)methanol (cas: 131747-45-0) belongs to pyridine derivatives. In contrast to benzene, Pyridine’s electron density is not evenly distributed over the ring, reflecting the negative inductive effect of the nitrogen atom. Many analogues of pyridine are known where N is replaced by other heteroatoms . Substitution of one C–H in pyridine with a second N gives rise to the diazine heterocycles (C4H4N2), with the names pyridazine, pyrimidine, and pyrazine.Computed Properties of C6H6BrNO