In 2011,Joshi, Girdhar; Adimurthy, Subbarayappa published 《Environment-Friendly Bromination of Aromatic Heterocycles Using a Bromide-Bromate Couple in an Aqueous Medium》.Industrial & Engineering Chemistry Research published the findings.HPLC of Formula: 13534-97-9 The information in the text is summarized as follows:
Selective monobromination of aromatic heterocyclic compounds through in-situ acid activation of 2:1 bromide/bromate couple as a benign brominating reagent is described. The in-situ acid activation of a bromide-bromate couple generates the reactive species BrOH, and it is proved to be an efficient for the bromination of various heterocycles under mild aqueous conditions without the use of any catalyst. Heterocycles that had electron-rich substituents provided good yields. In the part of experimental materials, we found many familiar compounds, such as 6-Bromopyridin-3-amine(cas: 13534-97-9HPLC of Formula: 13534-97-9)
6-Bromopyridin-3-amine(cas: 13534-97-9) belongs to anime. Left-handed and right-handed forms (mirror-image configurations, known as optical isomers or enantiomers) are possible when all the substituents on the central nitrogen atom are different (i.e., the nitrogen is chiral). With amines, there is extremely rapid inversion in which the two configurations are interconverted.HPLC of Formula: 13534-97-9