A new chelation-assistance mode for a ruthenium-catalyzed silylation at the C-H bond in aromatic ring with hydrosilanes was written by Kakiuchi, Fumitoshi;Igi, Kimitaka;Matsumoto, Mitsutaka;Hayamizu, Tomoo;Chatani, Naoto;Murai, Shinji. And the article was included in Chemistry Letters in 2002.Related Products of 4783-68-0 This article mentions the following:
Ru-catalyzed reactions of aromatic compounds having an amino group or a heteroaromatic ring as a directing group with triethylsilane gave the corresponding ortho silylated products in good to excellent yields. E.g., 2-benzylpyridine reacts with HSiEt3 in the presence of 6 mol% Ru3(CO)12 and norbornene/toluene to give 2-[2-(Et3Si)C6H4]C5H4N (77% yield) or 2-[2,6-(Et3Si)2C6H3]C5H4N (13% yield). In contrast previous results, in which the reactive substrates with π-conjugation between the hetero atom in the directing group and the C atom possessing the C-H bond to be cleaved were used, the present reaction proceeds in cases of substrates having no such π-conjugation. In the experiment, the researchers used many compounds, for example, 2-Phenoxypyridine (cas: 4783-68-0Related Products of 4783-68-0).
2-Phenoxypyridine (cas: 4783-68-0) belongs to pyridine derivatives. In contrast to benzene, Pyridine’s electron density is not evenly distributed over the ring, reflecting the negative inductive effect of the nitrogen atom. Many analogues of pyridine are known where N is replaced by other heteroatoms . Substitution of one C–H in pyridine with a second N gives rise to the diazine heterocycles (C4H4N2), with the names pyridazine, pyrimidine, and pyrazine.Related Products of 4783-68-0