Pyridine is colorless, but older or impure samples can appear yellow. 16133-25-8, formula is C5H4ClNO2S, Name is Pyridine-3-sulfonyl chloride. The pyridine ring occurs in many important compounds, including agrochemicals, pharmaceuticals, and vitamins. Historically, pyridine was produced from coal tar. Category: pyridine-derivatives.
Kalaramna, Pratibha;Goswami, Avijit research published 《 Temperature-Controlled Chemoselective Synthesis of Thiosulfonates and Thiocyanates: Novel Reactivity of KXCN (X = S, Se) towards Organosulfonyl Chlorides》, the research content is summarized as follows. An efficient chemoselective protocol has been developed for the synthesis of thiosulfonates RS(O)2SR (R = Me, CF3, Ph, thiophen-2-yl, etc.) and thiocyanates R1SCN (R1 = 2-ClC6H4, 3-pyridyl, 1H-indol-3-yl, etc.) by employing cost effective and com. available organosulfonyl chlorides RSO2Cl and R1SO2Cl with potassium thio-/selenocyanate. The strategy offered the thiosulfonates and thiocyanates selectively by tuning the equivalent of KSeCN and optimizing the reaction temperature On the other hand, thiosulfonates were obtained as sole products when organosulfonyl chlorides were treated with KSCN. Furthermore, the synthesis of phenyl(2,4,6-trimethoxyphenyl)sulfane and aryl(heteroaryl) thioethers I (R1 = Ph, 4-methylphenyl, 3-cyanophenyl, 5H,6H,7H-cyclopenta[c]pyridin-3-yl) was carried out as a part of synthetic application of newly prepared arylthiocyanates.
Category: pyridine-derivatives, Pyridine-3-sulfonyl chloride is a useful research compound. Its molecular formula is C5H4ClNO2S and its molecular weight is 177.61 g/mol. The purity is usually 95%.
Pyridine-3-sulfonyl chloride is a reagent used in the synthesis of pyrimidine derivatives with anti-proliferative activity against negative breast cancer cells.
Pyridine-3-sulfonyl chloride is a chemical compound that binds to the active site of cytochrome P450 enzymes. It can be used to study the effects of matrix effect on reaction solution. Pyridine-3-sulfonyl chloride has been shown to have an UV absorption spectrum with a maximum at 280 nm and a p450 activity that is proportional to the concentration of human serum. This compound has been shown to inhibit kinase domain in vitro assays, which may have clinical relevance in the treatment of obesity., 16133-25-8.