Synthetic Route of C5H6BNO2In 2022 ,《A Pyridine-based Donor-Acceptor Molecule: A Highly Reactive Organophotocatalyst that Enables the Reductive Cleavage of C-Br Bonds through Halogen Bonding》 appeared in ACS Catalysis. The author of the article were Kato, Natsuki; Nanjo, Takeshi; Takemoto, Yoshiji. The article conveys some information:
A pyridine-based donor-acceptor mol. that exhibited high reactivity as a visible-light photoredox catalyst. This photoredox catalyst enabled the formation of radicals from alkyl bromides, which were useful radical precursors that unfortunately do not perform well under reductive conditions, by a direct, photocatalytic reductive cleavage of the C-Br bond. A wide variety of alkyl bromides including unactivated ones could be used under ambient conditions without any addnl. activating agents to give the C-C coupling products in good yield. Mechanistic studies indicated that the photocatalyst interacts with alkyl bromides through halogen bonding and that the pyridine moiety was important for the progress of the reaction. In the experiment, the researchers used Pyridin-3-ylboronic acid(cas: 1692-25-7Synthetic Route of C5H6BNO2)
Pyridin-3-ylboronic acid(cas: 1692-25-7) belongs to pyridine. The basicity and metallophilic high donor number of these π-deficient systems has long favored them as ligands in metal catalysis. The last decade saw pyridine assume a stronger role as functional group for directed C–H oxidation/activation.Synthetic Route of C5H6BNO2