In 2019,Beilstein Journal of Organic Chemistry included an article by Kennedy, Sean H.; Gasonoo, Makafui; Klumpp, Douglas A.. Recommanded Product: 2,6-Dibromopyridine. The article was titled 《Superelectrophilic carbocations: preparation and reactions of a substrate with six ionizable groups》. The information in the text is summarized as follows:
A substrate was prepared having two triarylmethanol centers and four pyridine-type substituent groups. Upon ionization in Bronsted superacid CF3SO3H, the substrate underwent two types of reactions. In presence of only the superacid, highly ionized intermediate(s) provided a double cyclization product having two pyrido[1,2-a]indole rings I. With added benzene, an arylation product II was obtained. A mechanism was proposed involving tetra-, penta-, or hexacationic species. In addition to this study using 2,6-Dibromopyridine, there are many other studies that have used 2,6-Dibromopyridine(cas: 626-05-1Recommanded Product: 2,6-Dibromopyridine) was used in this study.
2,6-Dibromopyridine(cas: 626-05-1) belongs to pyridine. Pyridine’s structure is isoelectronic with that of benzene, but its properties are quite different. Pyridine is completely miscible with water, whereas benzene is only slightly soluble. Like all hydrocarbons, benzene is neutral (in the acid–base sense), but because of its nitrogen atom, pyridine is a weak base.Recommanded Product: 2,6-Dibromopyridine