Kobayashi, Yoshiro published the artcileStudies on the reaction of heterocyclic compounds. XV. N-Alkylation of 1,2,3,4-tetrahydro-5-methyl-1,6-naphthyridine, Application In Synthesis of 18437-58-6, the publication is Chemical & Pharmaceutical Bulletin (1976), 24(8), 1704-7, database is CAplus.
Alkylation of the 1-position of 5-methyl-1,2,3,4-tetrahydro-1,6-naphthyridine (I) does not proceed by ordinary methods. The UV absorption maximum of I shows a bathochromic shift on protonation. Considering this, alkylation was successfully carried out in the presence of NaNH2.
Chemical & Pharmaceutical Bulletin published new progress about 18437-58-6. 18437-58-6 belongs to pyridine-derivatives, auxiliary class Pyridine,Amine, name is 4-Amino-2-picoline, and the molecular formula is C6H8N2, Application In Synthesis of 18437-58-6.
Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem