The deoxydative substitution of pyridine N-oxides. Part XVI. Carbon-13 spectra of some tetrahydropyridines. The structure of the tetrahydropyridines from 3,5-lutidine 1-oxide and mercaptans in acetic anhydride was written by Kokosa, John M.;Chu, Ih;Bauer, Ludwig;Egan, Richard S.. And the article was included in Journal of Heterocyclic Chemistry in 1978.Computed Properties of C7H9NO This article mentions the following:
The reaction of 3,5-lutidine 1-oxide (I) with Me3CSH in Ac2O, with or without Et3N, was reinvestigated. There was obtained 2-tert-butylthio-3,5-lutidine as the major product, a small quantity of 5-(tert-butylthiomethyl)-3-picoline, 1-acetyl-2,3-diacetoxy-3,5-dimethyl-6-tert-butylthio-1,2,3,6-tetrahydropyridine (which represents a structure revision, F. M. Hershenson, et al., 1969) and 1-acetyl-2,6-dihydroxy-3-tert-butylthio-3,5-dimethyl-1,2,3,6-tetrahydropyridine. A similar reaction of I with 1-adamantyl mercaptan furnished 2-(1-adamantylthio)-3,5-lutidine and 1-acetyl-2,3-diacetoxy-3,5-dimethyl-6-(1-adamantylthio)-1,2,3,6-tetrahydropyridine. The structures of these new tetrahydropyridines were established primarily by 13C-NMR spectra. In the experiment, the researchers used many compounds, for example, 3,5-Dimethylpyridine 1-oxide (cas: 3718-65-8Computed Properties of C7H9NO).
3,5-Dimethylpyridine 1-oxide (cas: 3718-65-8) belongs to pyridine derivatives. Pyridine is diamagnetic and has a diamagnetic susceptibility of −48.7 × 10−6 cm3·mol−1.The molecular electric dipole moment is 2.2 debyes. The standard enthalpy of formation is 100.2 kJ·mol−1 in the liquid phase and 140.4 kJ·mol−1 in the gas phase. Several pyridine derivatives play important roles in biological systems. While its biosynthesis is not fully understood, nicotinic acid (vitamin B3) occurs in some bacteria, fungi, and mammals.Computed Properties of C7H9NO