Kuduk, Scott D.’s team published research in Organic Letters in 7 | CAS: 847225-56-3

Organic Letters published new progress about 847225-56-3. 847225-56-3 belongs to pyridine-derivatives, auxiliary class Pyridine,Fluoride,Nitrile, name is 4-Fluoropicolinonitrile, and the molecular formula is C6H3FN2, Safety of 4-Fluoropicolinonitrile.

Kuduk, Scott D. published the artcileTetrabutylammonium salt induced denitration of nitropyridines: synthesis of fluoro-, hydroxy-, and methoxypyridines, Safety of 4-Fluoropicolinonitrile, the publication is Organic Letters (2005), 7(4), 577-579, database is CAplus and MEDLINE.

An efficient method for the synthesis of fluoropyridines by the fluorodenitration reaction is reported. The reaction was mediated by tetrabutylammonium fluoride under mild conditions without undue regard to the presence of water. The fluorodenitration was general for 2- or 4-nitro-substituted pyridines, while 3-nitropyridines required attendant electron-withdrawing groups for the reaction to proceed efficiently. Nitropyridines also underwent hydroxy- and methoxydenitration under mild conditions in the presence of the corresponding tetrabutylammonium species.

Organic Letters published new progress about 847225-56-3. 847225-56-3 belongs to pyridine-derivatives, auxiliary class Pyridine,Fluoride,Nitrile, name is 4-Fluoropicolinonitrile, and the molecular formula is C6H3FN2, Safety of 4-Fluoropicolinonitrile.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem