Pyridine is a basic heterocyclic organic compound with the chemical formula C5H5N. It is structurally related to benzene, with one methine group (=CH−) replaced by a nitrogen atom. 31181-90-5, formula is C6H4BrNO, Name is 5-Bromopicolinaldehyde. It is a highly flammable, weakly alkaline, water-miscible liquid with a distinctive, unpleasant fish-like smell. Computed Properties of 31181-90-5.
Kurhade, Santosh;Diekstra, Elmar;Sutanto, Fandi;Kurpiewska, Katarzyna;Kalinowska-Tluscik, Justyna;Doemling, Alexander research published 《 Multicomponent Reaction Based Synthesis of 1-Tetrazolylimidazo[1,5-a]pyridines》, the research content is summarized as follows. Tetrazolyl imidazo[1,5-a]pyridines I [R = PhCH2, PhCH2CH2, t-Bu, cyclohexyl, 4-PhCH2OC6H4CH2, 2-furanmethyl, 3-indolylethyl, 3-(phthalimidyl)propyl, 3-ClC6H4CH2NHCOCH2, 4-MeOC6H4, 2,4,6-Me3C6H2, t-BuCH2CMe2, 1,3-benzodioxole-5-methyl; R1 = Me, t-Bu, Ph, HO2C(CH2)3, MeO2C(CH2)3, MeSCH2CH2, cyclohexylmethyl, 4-FC6H4CH2, 4-ClC6H4, cyclopropyl, 2-FC6H4CH2, 2-thienyl, (E)-2-(2-furyl)ethenyl, 4-acetyl-1-piperidinyl, PhCH2CH(NHAc), Ph] were prepared by Ugi-azide multicomponent condensation reactions of Me3SiN3, Ph3CNH2, 2-pyridinecarboxaldehydes, and isonitriles RN+C– [R = PhCH2, PhCH2CH2, t-Bu, cyclohexyl, 4-PhCH2OC6H4CH2, 2-furanmethyl, 3-indolylethyl, 3-(phthalimidyl)propyl, 3-ClC6H4CH2NHCOCH2, 4-MeOC6H4, 2,4,6-Me3C6H2, t-BuCH2CMe2, 1,3-benzodioxole-5-methyl] , followed by detritylation and cyclocondensation of the intermediate (tetrazolyl)pyridinemethanamine hydrochlorides with carboxylic acids, acyl anhydrides, or acid chlorides. Using this method, a guanylate cyclase inhibitor was prepared by a more concise route than previous syntheses.
Computed Properties of 31181-90-5, 5-Bromopyridine-2-carbaldehyde is a useful research compound. Its molecular formula is C6H4BrNO and its molecular weight is 186.01 g/mol. The purity is usually 95%.
5-Bromopyridine-2-carbaldehyde is a water soluble organic molecule that has been shown to inhibit the mitochondrial respiratory chain. It is a structural analog of the natural substrate for mitochondrial cytochrome c oxidase, 5-aminolevulinic acid. This compound has been shown to be selective against cancer cells and has anti-viral properties. The photophysical properties of 5-bromopyridine-2-carbaldehyde have been studied extensively. The fluorescence quantum yield of this molecule in aqueous solution is 0.06%., 31181-90-5.