Lauzon, Samuel; Caron, Laurent; Ollevier, Thierry published their research in Organic Chemistry Frontiers in 2021. The article was titled 《Efficient stereoselective synthesis of chiral 3,3′-dimethyl-(2,2′-bipyridine)-diol ligand and applications in FeII-catalysis》.COA of Formula: C6H6BrN The article contains the following contents:
A seven step synthesis of a chiral 2,2′-bipyridinediol ligand with 3,3′-dimethyl substituents was achieved starting from com. available materials. The O2-mediated oxidative homocoupling reaction of a chiral pyridine N-oxide was demonstrated to be the key step to prepare the S,S enantiomer of the title ligand with excellent stereoselectivities, i.e., 99% de and >99.5% ee. An unusual heptacoordination of FeII when complexed with the chiral 2,2′-bipyridinediol ligand was highlighted from single crystal diffraction anal. Steric strain due to the 3,3′-dimethyl groups was revealed from the structural anal. of the obtained FeII complex. Asym. induction using this chiral 3,3′-dimethyl-(2,2′-bipyridine)-diol ligand was studied in the Mukaiyama aldol and thia-Michael reactions. An increase of chiral induction in the latter one was achieved using the FeII catalyst made from newly synthesized ligand vs. Bolm’s ligand. After reading the article, we found that the author used 2-Bromo-5-methylpyridine(cas: 3510-66-5COA of Formula: C6H6BrN)
2-Bromo-5-methylpyridine(cas: 3510-66-5) belongs to pyridine. Pyridines are often used as catalysts or reagents; particular notice has been paid recently to how pyridine coordinates to metal centers enabling a wide range of valuable reactions. COA of Formula: C6H6BrN