Heteroaryl and cycloalkyl sulfonamide hydroxamic acid inhibitors of matrix metalloproteinases was written by Levin, J. I.;Gu, Y.;Nelson, F. C.;Zask, A.;DiJoseph, J. F.;Sharr, M. A.;Sung, A.;Jin, G.;Cowling, R.;Chanda, P.;Cosmi, S.;Hsiao, C.-L.;Edris, W.;Wilhelm, J.;Killar, L. M.;Skotnicki, J. S.. And the article was included in Bioorganic & Medicinal Chemistry Letters in 2001.Synthetic Route of C7H10N2O2 This article mentions the following:
Heteroaryl and cycloalkyl sulfonamide-hydroxamic acid MMP inhibitors were investigated. Of these, the pyridyl analog I is the most potent and selective inhibitor of MMP-9 and MMP-13 in vitro. In the experiment, the researchers used many compounds, for example, 3-Amino-2,6-dimethoxypyridine (cas: 28020-37-3Synthetic Route of C7H10N2O2).
3-Amino-2,6-dimethoxypyridine (cas: 28020-37-3) belongs to pyridine derivatives. In contrast to benzene, Pyridine’s electron density is not evenly distributed over the ring, reflecting the negative inductive effect of the nitrogen atom. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Synthetic Route of C7H10N2O2