ãA simple and efficient asymmetric hydrogenation of heteroaromatic ketones with iridium catalyst composed of chiral diamines and achiral phosphinesã?was written by Li, Chun; Lu, Xunhua; Wang, Mengna; Zhang, Ling; Jiang, Jian; Yan, Shunfa; Yang, Yuanyong; Zhao, Yonglong; Zhang, Lin. HPLC of Formula: 1122-54-9 And the article was included in Tetrahedron Letters in 2020. The article conveys some information:
An efficient iridium catalyst composed of a simple and com. available o-methoxytriphenylphosphine and 9-Amino (9-deoxy) epi-cinchonine was applied to the asym. hydrogenation of heteroaromatic ketones. A range of simple heteroaromatic ketones were hydrogenated with good to excellent enantioselectivities and high activities. In particular, thiophene ketones and furyl ketones furnished 98.6% ee with up to 2.18 x 104(1/h) TOF. This catalytic system was of practical value. In the experiment, the researchers used many compounds, for example, 4-Acetylpyridine(cas: 1122-54-9HPLC of Formula: 1122-54-9)
4-Acetylpyridine(cas: 1122-54-9) belongs to pyridine. Pyridines form stable salts with strong acids. Pyridine itself is often used to neutralize acid formed in a reaction and as a basic solvent. HPLC of Formula: 1122-54-9