Product Details of 100-54-9《Proximity Effect in Uranyl Coordination of the Cucurbit[6]uril-Bipyridinium Pseudorotaxane Ligand for Promoting Host-Guest Synergistic Chelating》 was published in 2021. The authors were Li, Fei-ze;Geng, Jun-shan;Hu, Kong-qiu;Yu, Ji-pan;Liu, Ning;Chai, Zhi-fang;Mei, Lei;Shi, Wei-qun, and the article was included in《Inorganic Chemistry》. The author mentioned the following in the article:
The authors proposed regulating uranyl coordination behavior of cucurbituril-bipyridinium pseudorotaxane ligand by using meta-functionalized bipyridinium dicarboxylate guest. A tailored pseudorotaxane precursor involving 1,1′-(hexane-1,6-diyl)bis(3-cyanopyridin-1-ium) bromide (C6BPCN3) and cucurbit[6]uril (CB[6]) has been designed and synthesized. Through in situ hydrolysis of the pseudorotaxane ligands and their coordination assembly with uranyl cations, seven new uranyl-rotaxane coordination polymers URCP1-URCP7 were obtained under hydrothermal conditions in the presence of different anions. The variation of carboxylate groups from para- to meta-position affected the coordination of the meta-functionalized pseudorotaxane linkers, which are enriched from simple guest-only binding to host-guest simultaneous coordination and synergistic chelating. This effective regulation on uranyl coordination of supramol. pseudorotaxane can be attributed to the proximity effect, which refers to the meta-position carboxyl group being spatially closer to the portal carbonyl group of CB[6]. Also, by combining other regulation methods such as introducing competing counterions and modulating solution acidity, the nuclearity of the uranyl center and the coordination patterns of the pseudorotaxane ligand can be diversely tuned, which subsequently exert great influence on the final dimensionality of resultant uranyl compounds This work presents a large diversity of uranyl-based coordination polyrotaxane compounds with fascinating mech. interlocked components and, most importantly, provides a feasible approach to adjust and control the metal coordination behavior of the pseudorotaxane ligand that might expand the scope of application of such supramol. ligands.3-Cyanopyridine (cas: 100-54-9) were involved in the experimental procedure.
3-Cyanopyridine(cas: 100-54-9) also shows biological activity against autoimmune diseases, such as murine hepatitis, by inhibiting the proliferation of B cells and T cells.Product Details of 100-54-9 This drug is not effective against cancer cells because it does not inhibit DNA synthesis or protein synthesis.