Nickel-catalyzed C-O bond reduction of aryl and benzyl 2-pyridyl ethers was written by Li, Jing;Wang, Zhong-Xia. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2018.Product Details of 4783-68-0 This article mentions the following:
The reduction of aryl and benzyl 2-pyridyl ethers with sodium isopropoxide was carried out via nickel-catalyzed C-OPy bond cleavage, giving reductive products in reasonable to excellent yields. This method allowed the 2-pyridyloxy group to be directly removed with high efficiency, mild reaction conditions, and good compatibility of functional groups. In the experiment, the researchers used many compounds, for example, 2-Phenoxypyridine (cas: 4783-68-0Product Details of 4783-68-0).
2-Phenoxypyridine (cas: 4783-68-0) belongs to pyridine derivatives. Pyridine has a conjugated system of six π electrons that are delocalized over the ring. The molecule is planar and, thus, follows the Hückel criteria for aromatic systems. One of the examples of pyridines is the well-known alkaloid lithoprimidine, which is an A3 adenosine receptor antagonist and N,N-dimethylaminopyridine (DMAP) analog, commonly used in organic synthesis.Product Details of 4783-68-0