Ionic Liquid-Promoted Formylation of N(sp2)-Heteroarenes with CO2/H2 over Pd/C was written by Li, Ruipeng;Zhao, Yanfei;Wang, Huan;Li, Dongyang;Wu, Yunyan;Zhang, Hongye;Tang, Minhao;Liu, Zhimin. And the article was included in ACS Sustainable Chemistry & Engineering in 2021.HPLC of Formula: 626-64-2 This article mentions the following:
Ionic liquid (IL)-promoted formylation of N(sp2)-heteroarenes with CO2 and H2 to produce formamides over the Pd/C nanocatalyst were studied. It was found that the combination of Pd/C with CO2-reactive IL, for example, tetrabutylphosphonium succinimide ([P4444][Suc]), achieved the hydrogenation of N(sp2)-heteroarenes and subsequent formylation with CO2/H2. A mechanism investigation indicated that [P4444][Suc] was simultaneously activated CO2 and N-heteroarenes via by forming carbamate and hydrogen bonds, resp.; meanwhile, it modified the catalytic activity of metal Pd via electron transfer, thus accomplished the production of formamides from N(sp2)-heteroarenes and CO2/H2 in combination with Pd/C. This catalytic system was tolerant to a wide substrate scope, afforded the corresponding formamides in moderate to high yields. The high efficacy enabled the designed IL-Pd/C catalytic system of high practical potential. In the experiment, the researchers used many compounds, for example, Pyridin-4-ol (cas: 626-64-2HPLC of Formula: 626-64-2).
Pyridin-4-ol (cas: 626-64-2) belongs to pyridine derivatives. The ring atoms in the pyridine molecule are sp2-hybridized. The nitrogen is involved in the π-bonding aromatic system using its unhybridized p orbital. The lone pair is in an sp2 orbital, projecting outward from the ring in the same plane as the σ bonds. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. HPLC of Formula: 626-64-2