Li, Xue; Bai, Fang; Liu, Chaogan; Ma, Xiaowei; Gu, Chengzhi; Dai, Bin published their research in Organic Letters in 2021. The article was titled 《Selective Electrochemical Oxygenation of Alkylarenes to Carbonyls》.Safety of 4-Acetylpyridine The article contains the following contents:
An efficient electrochem. method for benzylic C(sp3)-H bond oxidation has been developed. A variety of methylarenes, e.g., p-chlorotoluene, methylheteroarenes, e.g., 6-methylquinoline and benzylic (hetero)methylenes, e.g., p-ethyltoluene could be converted into the desired aryl aldehydes, e.g., 4-chlorobenzaldehyde/e.g., quinoline-6-carbaldehyde and aryl ketones, e.g., 1-(p-tolyl)ethan-1-one in moderate to excellent yields in an undivided cell, using O2 as the oxygen source and lutidinium perchlorate as an electrolyte. On the basis of cyclic voltammetry studies, 18O labeling experiments, and radical trapping experiments, a possible single-electron transfer mechanism has been proposed for the electrooxidation reaction. The results came from multiple reactions, including the reaction of 4-Acetylpyridine(cas: 1122-54-9Safety of 4-Acetylpyridine)
4-Acetylpyridine(cas: 1122-54-9) belongs to pyridine. Pyridine is widely used in the precursor to agrochemicals and pharmaceuticals. Also, it is used as an important reagent and organic solvent.Safety of 4-Acetylpyridine