Enabling Catalytic Arene C-H Amidomethylation via Bis(tosylamido)methane as a Sustainable Formaldimine Releaser was written by Li, Zhong-Yuan;Chaminda Lakmal, Hetti Handi;Cui, Xin. And the article was included in Organic Letters in 2019.Application In Synthesis of 2-(m-Tolyl)pyridine This article mentions the following:
2-Arylpyridines and aryl N-heterocycles such as 2-phenylpyridine underwent regioselective directed tosylaminomethylation with bis(tosylamino)methane as the formaldimine source in the presence of [Ru(p-cymene)Cl2]2, NaOAc, and Na2CO3 in 1,4-dioxane to yield mono(tosylaminomethyl)aryl pyridines such as I. Using the method, a dihydrobenzonaphthyridine and a dihydropyridobenzazepine were prepared In the experiment, the researchers used many compounds, for example, 2-(m-Tolyl)pyridine (cas: 4373-61-9Application In Synthesis of 2-(m-Tolyl)pyridine).
2-(m-Tolyl)pyridine (cas: 4373-61-9) belongs to pyridine derivatives. In contrast to benzene, Pyridine’s electron density is not evenly distributed over the ring, reflecting the negative inductive effect of the nitrogen atom. Halopyridines are particularly attractive synthetic building blocks in a variety of cross-coupling methods, including the Suzuki-Miyaura cross-coupling reaction.Application In Synthesis of 2-(m-Tolyl)pyridine