On March 12, 2022, Lin, Fengbin; Chen, Shida; Song, Yunhe; Li, Fei; Wang, Wei; Zhao, Zhenni; Gao, Xinbo; Wang, Peiyuan; Jin, Ling; Liu, Yuhong; Chen, Meiling; Liang, Xiaohong; Yang, Bin; Ning, Guili; Cheng, Ching-Yu; Healey, Paul R; Park, Ki Ho; Zangwill, Linda M; Aung, Tin; Ohno-Matsui, Kyoko; Jonas, Jost B; Weinreb, Robert N; Zhang, Xiulan; Glaucoma Suspects with High Myopia Study Group published an article.COA of Formula: C20H24N2O4 The title of the article was Classification of Visual Field Abnormalities in Highly Myopic Eyes without Pathologic Change.. And the article contained the following:
PURPOSE: To develop a classification system of visual field (VF) abnormalities in highly myopic eyes with and without glaucoma. DESIGN: Secondary analysis of VF data from a longitudinal cohort study. PARTICIPANTS: One thousand eight hundred ninety-three VF tests from 1302 eyes (825 individuals). METHODS: All participants underwent VF testing (Humphrey 24-2 Swedish interactive threshold algorithm standard program; Carl Zeiss Meditec) and detailed ophthalmic examination. A comprehensive set of VF defect patterns was defined via observation of the 1893 VF reports, literature review, and consensus meetings. The classification system comprised 4 major types of VF patterns, including normal type, glaucoma-like defects (paracentral defect, nasal step, partial arcuate defect, arcuate defect), high myopia-related defects (enlarged blind spot, vertical step, partial peripheral rim, nonspecific defect), and combined defects (nasal step with enlarged blind spot). A subset (n = 1000) of the VFs was used to evaluate the interobserver and intraobserver agreement and weighted κ values of the classification system by 2 trained readers. The prevalence of various VF patterns and their associated factors were determined. MAIN OUTCOME MEASURES: The classification of VF in highly myopic eyes and its associated risk factors. RESULTS: We found that normal type, glaucoma-like defects, high myopia-related defects, and combined defects accounted for 74.1%, 10.8%, 15.0%, and 0.1% of all unique VF tests, respectively. The interobserver and intraobserver agreements were > 89%, and the corresponding κ values were 0.86 or more between readers. Both glaucoma-like and high myopia-related VF defects were associated with older age (odds ratios [ORs], 1.07 [95% confidence interval (CI), 1.04-1.10; P < 0.001] and 1.06 [95% CI, 1.04-1.10; P < 0.001]) and longer axial length (ORs, 1.65 [95% CI, 1.32-2.07; P < 0.001] and 1.37 [95% CI, 1.11-1.68; P = 0.003]). Longer axial length showed a stronger effect on the prevalence of glaucoma-like VF defects than on the prevalence of high myopia-related VF defects (P = 0.036). CONCLUSIONS: We propose a new and reproducible classification system of VF abnormalities for nonpathologic high myopia. Applying a comprehensive classification system will facilitate communication and comparison of findings among studies. The experimental process involved the reaction of N,N-Dimethyl-3-phenyl-3-(pyridin-2-yl)propan-1-amine maleate(cas: 132-20-7).COA of Formula: C20H24N2O4
The Article related to glaucoma: complications, humans, intraocular pressure, longitudinal studies, myopia: complications, myopia: diagnosis, myopia: epidemiology, optic disk: pathology, retrospective studies, scotoma: diagnosis, vision disorders: pathology, visual field tests, visual fields and other aspects.COA of Formula: C20H24N2O4