Photoredox catalyzed dealkylative aromatic halogen substitution with tertiary amines was written by Lipilin, Dmitry L.;Frumkin, Alexander E.;Tyurin, Alexey Y.;Levin, Vitalij V.;Dilman, Alexander D.. And the article was included in Molecules in 2021.Application In Synthesis of 2,3,4,5,6-Perfluoropyridine The following contents are mentioned in the article:
A reaction of aromatic halides bearing electron-withdrawing groups with tertiary amines in the presence of an iridium catalyst under blue light irradiation is described. Products of the aromatic substitution of the halide by the dialkylamino fragment are obtained. The interaction of aryl radicals with tertiary amines to generate zwitterionic radical species is believed to be the key factor responsible for the reaction efficiency. This study involved multiple reactions and reactants, such as 2,3,4,5,6-Perfluoropyridine (cas: 700-16-3Application In Synthesis of 2,3,4,5,6-Perfluoropyridine).
2,3,4,5,6-Perfluoropyridine (cas: 700-16-3) belongs to pyridine derivatives. Pyridine has a conjugated system of six π electrons that are delocalized over the ring. The molecule is planar and, thus, follows the Hückel criteria for aromatic systems. Pyridine groups exist in countless molecules, and their applications include catalysis, drug design, molecular recognition, and natural product synthesis.Application In Synthesis of 2,3,4,5,6-Perfluoropyridine