Photochemistry of pyridine N-oxides was written by Lohse, Christian;Hagedorn, Linda;Albini, Angelo;Fasani, Elisa. And the article was included in Tetrahedron in 1988.Application In Synthesis of 3,5-Dimethylpyridine 1-oxide This article mentions the following:
Photolysis of pyridine N-oxide in aqueous basic solution yields the anion of 5-hydroxypentadienenitrile. Kinetic data are obtained from flash photolytic measurements. The reaction is extended to twenty substituted pyridine N-oxides, including deuterated derivatives, as well as 10 other exptl. conditions (amines as the base in organic solvents). The results can be rationalized as involving primary photorearrangement to open-chain nitrene (I) (τ 62 ms in water) , which rearranges in low yield to 2-formylpyrrole or undergoes polymerization to tars. In the presence of bases, this intermediate is efficiently deprotonated to the anion of 5-hydroxypentadienenitrile (k = 690 M-1s-1 for the reaction of I with OH–). The relation of this new rearrangement to other photoprocesses of heterocyclic N-oxides is discussed. In the experiment, the researchers used many compounds, for example, 3,5-Dimethylpyridine 1-oxide (cas: 3718-65-8Application In Synthesis of 3,5-Dimethylpyridine 1-oxide).
3,5-Dimethylpyridine 1-oxide (cas: 3718-65-8) belongs to pyridine derivatives. Pyridine is diamagnetic and has a diamagnetic susceptibility of −48.7 × 10−6 cm3·mol−1.The molecular electric dipole moment is 2.2 debyes. The standard enthalpy of formation is 100.2 kJ·mol−1 in the liquid phase and 140.4 kJ·mol−1 in the gas phase. Many analogues of pyridine are known where N is replaced by other heteroatoms . Substitution of one C–H in pyridine with a second N gives rise to the diazine heterocycles (C4H4N2), with the names pyridazine, pyrimidine, and pyrazine.Application In Synthesis of 3,5-Dimethylpyridine 1-oxide