Synthesis and antiviral activity evaluation of some novel acyclic C-nucleosides was written by Lougiakis, Nikolaos;Marakos, Panagiotis;Poul, Nicole;Balzarini, Jan. And the article was included in Chemical & Pharmaceutical Bulletin in 2008.Application In Synthesis of 4-Methoxy-2-methylpyridine This article mentions the following:
The preparation of novel 5-amino or 7-hydroxy substituted pyrazolo[4,3-b]pyridine and pyrazolo[3,4-c]pyridine acyclic C-nucleosides is described. Their synthesis was carried out by condensation of suitably substituted lithiated picolines with 2-benzyloxyethoxymethylchloride followed by pyrazole ring annulation. The compounds were evaluated for their antiviral activity against a wide panel of viruses, but were found inactive at subtoxic concentrations In the experiment, the researchers used many compounds, for example, 4-Methoxy-2-methylpyridine (cas: 24103-75-1Application In Synthesis of 4-Methoxy-2-methylpyridine).
4-Methoxy-2-methylpyridine (cas: 24103-75-1) belongs to pyridine derivatives. Pyridine’s the lone pair does not contribute to the aromatic system but importantly influences the chemical properties of pyridine, as it easily supports bond formation via an electrophilic attack. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Application In Synthesis of 4-Methoxy-2-methylpyridine