Lu, Jing et al. published their research in Journal of the American Chemical Society in 2021 | CAS: 626-64-2

Pyridin-4-ol (cas: 626-64-2) belongs to pyridine derivatives. Pyridine has a dipole moment and a weaker resonant stabilization than benzene (resonance energy 117 kJ璺痬ol閳? in pyridine vs. 150 kJ璺痬ol閳? in benzene). Pyridine derivatives are also useful as small-molecule 浼?helix mimetics that inhibit protein-protein interactions, as well as functionally selective GABA ligands.Quality Control of Pyridin-4-ol

Discovery of NLO Semiorganic (C5H6ON)+(H2PO4)–: Dipole Moment Modulation and Superior Synergy in Solar-Blind UV Region was written by Lu, Jing;Liu, Xin;Zhao, Min;Deng, Xue-Bin;Shi, Ke-Xin;Wu, Qian-Ru;Chen, Ling;Wu, Li-Ming. And the article was included in Journal of the American Chemical Society in 2021.Quality Control of Pyridin-4-ol This article mentions the following:

We herein report a novel semiorg. NLO material, (C5H6ON)+(H2PO4)–, 4HPP, showing promising excellent properties in the important solar-blind UV region where LAP and its deuterated form DLAP are the only commercialized semiorg. materials. For the first time, the 4-hydroxypyridine (4HP+, (C5H6ON)+) cation is identified as NLO active and how to eliminate the dipole-dipole interaction to avoid the unwanted center-symmetry-trap caused by the polar-induced susceptibility is well demonstrated. Remarkably, 4HPP exhibits competitive and even better properties compared with LAP that include better thermal stability (decomposition at 166 vs 112鎺矯 of LAP); wider transparency range (0.26-1.50娓璵); very strong SHG response (3 x KDP); a suitable large birefringence (铻杗cal = 0.25 vs 0.075 of LAP); and a high laser-induced damage threshold (2.2 x KDP). First-principles calculations show that the 锜?conjugated organic (4HP)+ cation governs the optical anisotropy, whereas the synergy of the organic and inorganic moieties dominates the SHG process. Our discovery points out a new path for the rational design of high performance semiorg. materials that require an acentric structure. In the experiment, the researchers used many compounds, for example, Pyridin-4-ol (cas: 626-64-2Quality Control of Pyridin-4-ol).

Pyridin-4-ol (cas: 626-64-2) belongs to pyridine derivatives. Pyridine has a dipole moment and a weaker resonant stabilization than benzene (resonance energy 117 kJ璺痬ol閳? in pyridine vs. 150 kJ璺痬ol閳? in benzene). Pyridine derivatives are also useful as small-molecule 浼?helix mimetics that inhibit protein-protein interactions, as well as functionally selective GABA ligands.Quality Control of Pyridin-4-ol

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem