《Transition-metal-free direct nucleophilic substitution of carboranyllithium and 2-halopyridines》 was written by Lu, Ju-You; Zhao, Bo; Du, Yongmei; Yang, Jianxin; Lu, Jian. Electric Literature of C6H6BrNThis research focused ontransition metal free nucleophilic substitution carboranyl lithium halopyridine; pyridinyl carborane preparation. The article conveys some information:
A practical and efficient C(cage)-heteroarylation of carborane is presented, via direct nucleophilic substitution of carboranyllithium with 2-halopyridines. This reaction does not need the aid of any transition metal and utilizes readily available carboranyllithium nucleophiles, thereby avoiding transmetalation of carboranyllithium. The process exhibits a broad scope, and a vast array of 2-halopyridines have proven to be suitable substrates. The method serves as a complement to C(cage)-arylation reactions and may find wide applications in materials science and medicinal and coordination chem. The experimental part of the paper was very detailed, including the reaction process of 2-Bromo-5-methylpyridine(cas: 3510-66-5Electric Literature of C6H6BrN)
2-Bromo-5-methylpyridine(cas: 3510-66-5) belongs to pyridine. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Additionally, pyridine-based natural products continue to be discovered and studied for their properties and to understand their biosynthesis.Electric Literature of C6H6BrN