Luo, Mu-Jia; Ouyang, Xuan-Hui; Zhu, Yan-Ping; Li, Yang; Li, Jin-Heng published their research in Green Chemistry in 2021. The article was titled 《Metal-free electrochemical [3 + 2] heteroannulation of anilines with pyridines enabled by dual C-H radical aminations》.Related Products of 1122-54-9 The article contains the following contents:
An unprecedented metal-/external-oxidant-free electrochem. intermol. [3+2] heteroannulation of anilines with electron-deficient pyridines enabled by dual C-H radical aminations for producing functionally diverse benzo[4,5]imidazo[1,2-a]pyridines was described. The site-selectivity of aminations of aryl C(sp2)-H bonds relied on the electronic effect of two reaction partners: each contributed two reactive sites (a C(sp2)-H bond and a nitrogen atom-based functional group) and the electron-withdrawing groups at the 4 position of the pyridine ring were crucial. Mechanistic studies have shown that this method sequence consisted of the generation of the nitrogen-centered radical (NCR) and the pyridine radical anion, radical coupling, and dual C-N aminations. In the experiment, the researchers used 4-Acetylpyridine(cas: 1122-54-9Related Products of 1122-54-9)
4-Acetylpyridine(cas: 1122-54-9) belongs to pyridine. Pyridine is widely used in the precursor to agrochemicals and pharmaceuticals. Also, it is used as an important reagent and organic solvent.Related Products of 1122-54-9