Luo, Yun-Cheng; Tong, Fei-Fei; Zhang, Yanxia; He, Chun-Yang; Zhang, Xingang published the artcile< Visible-Light-Induced Palladium-Catalyzed Selective Defluoroarylation of Trifluoromethylarenes with Arylboronic Acids>, Application of C6H4F3N, the main research area is trifluoromethylarene arylboronic acid palladium defluoroarylation cross coupling oxidative addition; diaryldifluoromethane preparation selective photochem.
An unprecedented excited-state palladium catalysis strategy for selective defluoroarylation of trifluoromethylarenes with arylboronic acids was reported. This visible-light-induced palladium-catalyzed cross-coupling proceeded under mild reaction conditions and allowed transformation of a variety of arylboronic acids and ArCF3. Preliminary mechanistic studies revealed that the oxidative addition of the C(sp3)-F bond in ArCF3 to excited-state palladium(0) via a single electron transfer pathway is responsible for the C(sp3)-F bond activation.
Journal of the American Chemical Society published new progress about Aralkyl fluorides Role: PRP (Properties), SPN (Synthetic Preparation), PREP (Preparation). 3796-23-4 belongs to class pyridine-derivatives, and the molecular formula is C6H4F3N, Application of C6H4F3N.