Luo, Yuncong; Jiang, Shengjie; Xu, Xin published the artcile< Yttrium-Catalyzed ortho-Selective C-H Borylation of Pyridines with Pinacolborane>, Related Products of 581-47-5, the main research area is yttrium catalyzed carbon hydrogen borylation pyridine pinacolborane; crystal mol structure pyridyl boronate; pentamethylcyclopentadienyl yttrium pyridyl boronate intermediate preparation crystal mol structure; Borylation; C−H Activation; Pyridines; Regioselectivity; Yttrium.
This work reports a site-selective C-H borylation of pyridines at the ortho-position with pinacolborane enabled by an yttrocene catalyst. The reaction provides a new family of 2-pyridyl boronates with a broad substrate scope and high atom efficiency. The resultant boronates were able to undergo a variety of transformations, e.g., oxidation, Suzuki-Miyaura coupling, Chan-Lam amination and etherification. Catalytic intermediates, including ortho-C-H metalated and borylated complexes, were isolated from stoichiometric experiments and confirmed by single-crystal x-ray diffraction.
Angewandte Chemie, International Edition published new progress about Amination. 581-47-5 belongs to class pyridine-derivatives, and the molecular formula is C10H8N2, Related Products of 581-47-5.