I found the field of Pharmacology & Pharmacy very interesting. Saw the article Design and Synthesis of Pyrrolidine-based Fragments That Sample Three-dimensional Molecular Space published in 2019.0. Formula: C6H5NO, Reprint Addresses Garner, P (corresponding author), Washington State Univ, Dept Chem, Pullman, WA 99164 USA.; Cox, PB (corresponding author), AbbVie Inc, Discovery Chem & Technol, 1 North Waukegan Rd, N Chicago, IL 60064 USA.. The CAS is 500-22-1. Through research, I have a further understanding and discovery of 3-Pyridinecarboxaldehyde
Fragment-based drug discovery (FBDD) is a well- established technology for lead compound generation in drug discovery. As this technology has evolved, the design of fragments for screening has also evolved to engender not just an understanding of the role of modulating the physicochemical properties of fragments (Rule of Three, Ro3) but also the importance and implications of incorporating shape and, in particular, 3D characteristics into fragments. Herein, we describe the design and synthesis of pyrrolidine-based fragments with good fragment-like (Ro3) physicochemical properties that effectively sample three-dimensional molecular space.
Formula: C6H5NO. About 3-Pyridinecarboxaldehyde, If you have any questions, you can contact Garner, P; Cox, PB; Rathnayake, U; Holloran, N; Erdman, P or concate me.
Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem