Mack, Arthur G.; Suschitzky, Hans; Wakefield, Basil J. published the artcile< Polyhaloaromatic compounds. Part 39. Synthesis of the bromo- and iodo-tetrachloropyridines>, Recommanded Product: 2,3,4,6-Tetrachloropyridine, the main research area is bromotetrachloropyridine; iodotetrachloropyridine; pyridine bromo tetrachloro.
The title compounds I (R = Br, iodo, R1 = R2 = Cl; R = R2 = Cl, R1 = Br, iodo; R = R1 = Cl, R2 = Br, iodo) were prepared via the corresponding pyridylhydrazines or pyridyllithium or -magnesium derivatives Thus, reaction of pentachloropyridine N-oxide with N2H4 in EtOH (reflux 2 h) gave 2,3,4,5-tetrachloro-6-hydrazinopyridine which with Br-HBr gave 60% I (R = Br, R1 = R2 = Cl). Metalation of 2,3,4,6-tetrachloropyridine with BuLi followed by reaction with Br and iodine gave 58% I (R = R2 = Cl, R1 = Br) and 60% I (R = R2 = Cl, R1 = iodo), resp. Reaction of pentachloropyridine in THF with Mg at -10° gave 2,3,5,6-tetrachloro-4-pyridylmagnesium chloride which reacted with Br (-75°) to give 61% I (R = R1 = Cl, R2 = Br).
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999) published new progress about 14121-36-9. 14121-36-9 belongs to class pyridine-derivatives, and the molecular formula is C5HCl4N, Recommanded Product: 2,3,4,6-Tetrachloropyridine.