On May 22, 2014, Magda, Darren; Xu, Jide; Butlin, Nathaniel G. published a patent.Product Details of 170235-18-4 The title of the patent was Preparation of di-macrocycles and their complexes for use in therapeutics and diagnostic applications. And the patent contained the following:
The invention relates to chem. compounds of formula I and complexes that can be used in therapeutic and diagnostic applications. Compounds of formula I wherein B1, B2, B3 and B4 are independently N, C, B, Si and P; F1 and F2 are independently H, (un)substituted alkyl, (un)substituted heteroaryl, (un)substituted aryl, etc.; L1 – L9 are independently (un)substituted alkyl, (un)substituted heteroalkyl, (un)substituted aryl, etc.; A1, A2, A3 and A4 are independently substituted aryl and (un)substituted heteroaryl; are claimed. Example compound II was prepared by a multistep procedure (procedure given). The invention compounds were evaluated for their metal chelation ability for use in therapeutic and diagnostic application (some data given). The experimental process involved the reaction of Methyl 6-bromo-5-methoxypicolinate(cas: 170235-18-4).Product Details of 170235-18-4
The Article related to dimacrocycle preparation complex therapeutic and diagnostic application, Heterocyclic Compounds (More Than One Hetero Atom): Eight- and Higher-Membered Rings and other aspects.Product Details of 170235-18-4