Product Details of 1539-42-0In 2021 ,《Strategic Evaluation of the Traceless Staudinger Ligation for Radiolabeling with the Tricarbonyl Core》 appeared in Molecules. The author of the article were Mamat, Constantin; Jentschel, Christian; Koeckerling, Martin; Steinbach, Joerg. The article conveys some information:
The traceless Staudinger ligation with its two variants is a powerful biorthogonal conjugation method not only for the connection of biomols., but also for the introduction of fluorescence- or radiolabels under mild reaction conditions. Herein, the strategic evaluation of the traceless Staudinger ligation for radiolabeling 99mTc using the fac-[Tc(CO)3]+ core is presented. A convenient and high-yielding three-step synthetic procedure of dipicolylamine-based phosphanols as ligands for the mild radiolabeling was developed. The labeling was accomplished using a tricarbonyl kit and a 99mTc-pertechnetate generator eluate showing 87% radiochem. conversion. The resp. rhenium-based, non-radioactive reference compounds were synthesized using (Et4N)2[Re(CO)3Br3] as precursor. All products were analyzed by NMR, MS, and elemental anal. Addnl. XRD analyses were performed. In addition to this study using Bis(pyridin-2-ylmethyl)amine, there are many other studies that have used Bis(pyridin-2-ylmethyl)amine(cas: 1539-42-0Product Details of 1539-42-0) was used in this study.
Bis(pyridin-2-ylmethyl)amine(cas: 1539-42-0) is a secondary amine with two picolyl substituents. The compound is a tridentate ligand in coordination chemistry and commonly used to produce Zn-based chemosensors/probes, such as Zinpry.Product Details of 1539-42-0